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What Is Low Retention？
Low Retention Pipette Tips are a type of pipette tip specifically designed to reduce liquid carryover. Compared with ordinary pipette tips, low retention rate tips significantly reduce the adsorption of liquid on the inner wall of the tip through special surface treatment or material selection, thereby improving the accuracy and repeatability of liquid transfer. This design is particularly suitable for handling high-value, low-volume or volatile liquid samples, such as DNA solutions, protein solutions, organic solvents, etc.
Features of low retention tips include:
Low surface tension: these pipette tips usually have lower surface tension, making it easier for liquid to fall off the inner wall of the tip, reducing the amount of residual liquid.
High Precision and Repeatability: Due to reduced liquid carryover, low retention filter tips enable more accurate liquid transfer, especially when processing small sample volumes, improving experimental accuracy and repeatability.
Strong compatibility: Low retention tips are generally compatible with various types of pipettes, including manual and electronic pipettes.
Key material selection and surface treatment technology:
Material selection:
Polypropylene (PP): This is a commonly used material with good chemical stability, high hydrophobicity, autoclavability, good transparency and softness. In addition, polypropylene has high purity and low Metal and leachate content, free of impurities, and can be sterilized by gamma and electron beam.
Surface treatment:
Low-residue surface treatment: The surface of the tip is specially hydrophobic, making it easier for liquid to slide off the tip surface and reducing residue. Some tips also have special coatings, such as silanization, to further reduce the adhesion of liquids.
